E2 Optimization For Multivalent 1c-SApNP Vaccine Design
The optimized HCV E2 core, with enhanced structural stability, can be displayed on self-assembling protein nanoparticles (1c-SApNP) as vaccine candidates and induce broad and potent neutralizing antibodies (bpNAbs) more effectively than E1E2 or E2 alone.
3 Nanoparticle Platforms & Their EM Images
The Vaccine Concept
Robust Production in Various Expression Systems
Mouse Immunization: Study Design
Longitudinal Analysis of HCV E2-specific Ab Titers